acetaminophen, diphenhydramine, and phenylephrine

Acetaminophen is a pain reliever and fever reducer.

Diphenhydramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of acetaminophen, diphenhydramine, and phenylephrine is used to treat runny or stuffy nose, sinus congestion, sneezing, itchy nose, itchy or watery eyes, sore throat, cough, headache, and pain or fever caused by allergies or the common cold.

This medication will not treat a cough that is caused by smoking, asthma, or emphysema.

Acetaminophen, diphenhydramine, and phenylephrine may also be used for other purposes not listed in this medication guide.

• What is acetaminophen, diphenhydramine, and phenylephrine?


• What is the most important information i should know about acetaminophen, diphenhydramine, and phenylephrine?


• What should i discuss with my healthcare provider before taking acetaminophen, diphenhydramine, and phenylephrine?


• How should i take acetaminophen, diphenhydramine, and phenylephrine?


• What happens if i miss a dose?


• What happens if i overdose?


• What should i avoid while taking acetaminophen, diphenhydramine, and phenylephrine?


• Acetaminophen, diphenhydramine, and phenylephrine side effects


• Acetaminophen, diphenhydramine, and phenylephrine dosing information


• What other drugs will affect acetaminophen, diphenhydramine, and phenylephrine?


• Where can i get more information?